StressCovidV1, Main, Exploration, bibRecord, 001C95

Pandemic and seasonal influenza: therapeutic challenges.

Identifieur interne : 001C95 ( Main/Exploration ); précédent : 001C94; suivant : 001C96

Pandemic and seasonal influenza: therapeutic challenges.

Auteurs : Matthew J. Memoli [États-Unis] ; David M. Morens ; Jeffery K. Taubenberger

Source :

Drug discovery today [ 1359-6446 ] ; 2008.

RBID : pubmed:18598914

Descripteurs français

KwdFr :
- Antiviraux (usage thérapeutique), Flambées de maladies, Grippe humaine (), Grippe humaine (épidémiologie), Humains, Infection croisée (), Infection croisée (traitement médicamenteux), Infection croisée (épidémiologie), Pharmacologie clinique, Saisons.
MESH :
- traitement médicamenteux : Infection croisée.
- usage thérapeutique : Antiviraux.
- épidémiologie : Grippe humaine, Infection croisée.
- Flambées de maladies, Grippe humaine, Humains, Infection croisée, Pharmacologie clinique, Saisons.

English descriptors

KwdEn :
- Antiviral Agents (therapeutic use), Cross Infection (complications), Cross Infection (drug therapy), Cross Infection (epidemiology), Disease Outbreaks, Humans, Influenza, Human (complications), Influenza, Human (epidemiology), Influenza, Human (therapy), Pharmacology, Clinical, Seasons.
MESH :
- chemical , therapeutic use : Antiviral Agents.
- complications : Cross Infection, Influenza, Human.
- drug therapy : Cross Infection.
- epidemiology : Cross Infection, Influenza, Human.
- therapy : Influenza, Human.
- Disease Outbreaks, Humans, Pharmacology, Clinical, Seasons.

Abstract

Influenza A viruses cause significant morbidity and mortality annually, and the threat of a pandemic underscores the need for new therapeutic strategies. Here, we briefly discuss novel antiviral agents under investigation, the limitations of current antiviral therapy and stress the importance of secondary bacterial infections in seasonal and pandemic influenza. Additionally, the lack of new antibiotics available to treat increasingly drug resistant organisms such as methicillin-resistant Staphylococcus aureus, pneumococci, Acinetobacter, extended spectrum beta-lactamase producing gram negative bacteria and Clostridium difficile is highlighted as an important component of influenza treatment and pandemic preparedness. Addressing these problems will require a multidisciplinary approach, which includes the development of novel antivirals and new antibiotics, as well as a better understanding of the role secondary infections play on the morbidity and mortality of influenza infection.

DOI: 10.1016/j.drudis.2008.03.024
PubMed: 18598914

Affiliations:

Le document en format XML

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<term>Disease Outbreaks</term>
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<term>Infection croisée (épidémiologie)</term>
<term>Pharmacologie clinique</term>
<term>Saisons</term>
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<term>Influenza, Human</term>
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<front><div type="abstract" xml:lang="en">Influenza A viruses cause significant morbidity and mortality annually, and the threat of a pandemic underscores the need for new therapeutic strategies. Here, we briefly discuss novel antiviral agents under investigation, the limitations of current antiviral therapy and stress the importance of secondary bacterial infections in seasonal and pandemic influenza. Additionally, the lack of new antibiotics available to treat increasingly drug resistant organisms such as methicillin-resistant Staphylococcus aureus, pneumococci, Acinetobacter, extended spectrum beta-lactamase producing gram negative bacteria and Clostridium difficile is highlighted as an important component of influenza treatment and pandemic preparedness. Addressing these problems will require a multidisciplinary approach, which includes the development of novel antivirals and new antibiotics, as well as a better understanding of the role secondary infections play on the morbidity and mortality of influenza infection.</div>
</front>
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Pandemic and seasonal influenza: therapeutic challenges.

Pandemic and seasonal influenza: therapeutic challenges.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration Stress et Covid
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